diff --git a/reference/mixin-arguments.rst b/reference/mixin-arguments.rst
index 388bb0c..8e12c9b 100644
--- a/reference/mixin-arguments.rst
+++ b/reference/mixin-arguments.rst
@@ -50,3 +50,5 @@ In all other cases the latter value replaces the former value.
     But passing these arguments to CMake would result in the latter value of
     ``CMAKE_C_FLAGS`` overwriting the former even though the user likely wanted
     both compiler options to be used.
+
+    Furthermore, the option values of a mixin used through the CLI override the default values of a :ref:`default file <configuration_defaults-yaml>`.
diff --git a/user/configuration.rst b/user/configuration.rst
index c44256c..8ca60a1 100644
--- a/user/configuration.rst
+++ b/user/configuration.rst
@@ -91,10 +91,12 @@ The following are a few examples (see e.g. ``colcon build --help``):
 
     The default value for the environment variable ``COLCON_HOME`` is pointing to the directory ``.colcon`` within the users home directory.
 
+.. _configuration_defaults-yaml:
+
 defaults.yaml
 -------------
 
-Default files are used to configure ``colcon`` behavior for all packages being operated on.
+Default files are used to configure the **default** ``colcon`` behavior for all packages being operated on.
 Multiple configuration files can be used to modify verb behavior without using the CLI:
 
 * If the configuration file ``$COLCON_HOME/defaults.yaml`` exists it is used to customize the default behavior of the CLI.
@@ -110,6 +112,10 @@ In the case of more than one nested verbs the key is the names separated by dots
 To specify configuration options *before* the first verb use an empty string key.
 The value is another dictionary containing the verb specific configuration.
 
+.. note::
+
+    When using a :doc:`mixin <../reference/mixin-arguments>` through the CLI, the mixin's option values override default values from a default file.
+
 Verb specific configuration
 ~~~~~~~~~~~~~~~~~~~~~~~~~~~