diff --git a/src/tests/issues.targets b/src/tests/issues.targets
index d14ab8edbdbc12..10aa30649463c3 100644
--- a/src/tests/issues.targets
+++ b/src/tests/issues.targets
@@ -590,6 +590,9 @@
         <ExcludeList Include="$(XunitTestBinBase)/GC/Scenarios/DoublinkList/dlstack/*">
             <Issue>Release only crash</Issue>
         </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/HardwareIntrinsics/General/Vector256/**">
+            <Issue>https://github.com/dotnet/runtime/issues/60154</Issue>
+        </ExcludeList>
     </ItemGroup>
 
     <!-- Unix arm32 specific -->
@@ -603,6 +606,9 @@
         <ExcludeList Include="$(XunitTestBinBase)/profiler/multiple/multiple/*">
             <Issue>https://github.com/dotnet/runtime/issues/57875</Issue>
         </ExcludeList>
+        <ExcludeList Include="$(XunitTestBinBase)/JIT/HardwareIntrinsics/General/Vector256/**">
+            <Issue>https://github.com/dotnet/runtime/issues/60154</Issue>
+        </ExcludeList>
     </ItemGroup>
 
     <!-- Tests that need to be triaged for vararg usage as that is not supported -->