diff --git a/.github/.trivyignore b/.github/.trivyignore
index a3242f56c5..1f9f11bd30 100644
--- a/.github/.trivyignore
+++ b/.github/.trivyignore
@@ -2,7 +2,7 @@
 # Ignored Vulnerabilities
 # =======================
 
-# Accepting risk due to Python 3.7 and 3.8 support.
+# Accepting risk due to Python 3.8 support.
 CVE-2025-50181
 
 # Not relevant, only affects Pyodide
diff --git a/.github/containers/Dockerfile b/.github/containers/Dockerfile
index c9e22a93cb..97fc1bf9c4 100644
--- a/.github/containers/Dockerfile
+++ b/.github/containers/Dockerfile
@@ -111,7 +111,7 @@ RUN echo 'eval "$(pyenv init -)"' >>${HOME}/.bashrc && \
     pyenv update
 
 # Install Python
-ARG PYTHON_VERSIONS="3.12 3.11 3.10 3.9 3.8 3.7 3.13 pypy3.10-7.3.17"
+ARG PYTHON_VERSIONS="3.13 3.12 3.11 3.10 3.9 3.8 pypy3.10-7.3.17"
 COPY --chown=0:0 --chmod=755 ./install-python.sh /tmp/install-python.sh
 RUN /tmp/install-python.sh && \
     rm /tmp/install-python.sh
diff --git a/.github/workflows/deploy.yml b/.github/workflows/deploy.yml
index 707b4fe3b0..0d6b7009f2 100644
--- a/.github/workflows/deploy.yml
+++ b/.github/workflows/deploy.yml
@@ -23,42 +23,6 @@ permissions:
   contents: read
 
 jobs:
-  build-linux-py3-legacy:
-    runs-on: ubuntu-24.04
-    strategy:
-      fail-fast: false
-      matrix:
-        wheel:
-          - cp37-manylinux
-          - cp37-musllinux
-
-    steps:
-      - uses: actions/checkout@08c6903cd8c0fde910a37f88322edcfb5dd907a8 # 5.0.0
-        with:
-          persist-credentials: false
-          fetch-depth: 0
-
-      - name: Setup QEMU
-        uses: docker/setup-qemu-action@29109295f81e9208d7d86ff1c6c12d2833863392 # 3.6.0
-
-      - name: Build Wheels
-        uses: pypa/cibuildwheel@8d945475ac4b1aac4ae08b2fd27db9917158b6ce # 2.17.0
-        env:
-          CIBW_PLATFORM: linux
-          CIBW_BUILD: "${{ matrix.wheel }}*"
-          CIBW_ARCHS_LINUX: x86_64 aarch64
-          CIBW_ENVIRONMENT: "LD_LIBRARY_PATH=/opt/rh/devtoolset-8/root/usr/lib64:/opt/rh/devtoolset-8/root/usr/lib:/opt/rh/devtoolset-8/root/usr/lib64/dyninst:/opt/rh/devtoolset-8/root/usr/lib/dyninst:/usr/local/lib64:/usr/local/lib"
-          CIBW_TEST_REQUIRES: pytest
-          CIBW_TEST_COMMAND: "PYTHONPATH={project}/tests pytest {project}/tests/agent_unittests -vx"
-
-      - name: Upload Artifacts
-        uses: actions/upload-artifact@ea165f8d65b6e75b540449e92b4886f43607fa02 # 4.6.2
-        with:
-          name: ${{ github.job }}-${{ matrix.wheel }}
-          path: ./wheelhouse/*.whl
-          if-no-files-found: error
-          retention-days: 1
-
   build-linux-py3:
     runs-on: ubuntu-24.04
     strategy:
@@ -151,7 +115,6 @@ jobs:
       attestations: write
 
     needs:
-      - build-linux-py3-legacy
       - build-linux-py3
       - build-sdist
 
diff --git a/THIRD_PARTY_NOTICES.md b/THIRD_PARTY_NOTICES.md
index 7aa68f22dd..2aceaea9fa 100644
--- a/THIRD_PARTY_NOTICES.md
+++ b/THIRD_PARTY_NOTICES.md
@@ -35,15 +35,6 @@ Distributed under the following license(s):
 * [The Apache License, Version 2.0 License](https://opensource.org/license/apache-2-0/)
 
 
-## [time.monotonic](newrelic/common/_monotonic.c)
-
-Copyright (c) 2001, 2002, 2003, 2004, 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013 Python Software Foundation; All Rights Reserved
-
-Distributed under the following license(s):
-
-* [Python Software Foundation](https://docs.python.org/3/license.html)
-
-
 ## [urllib3](https://pypi.org/project/urllib3)
 
 Copyright (c) 2008-2019 Andrey Petrov and contributors (see CONTRIBUTORS.txt)
diff --git a/newrelic/agent.py b/newrelic/agent.py
index 43f452832c..af98f03c55 100644
--- a/newrelic/agent.py
+++ b/newrelic/agent.py
@@ -15,56 +15,9 @@
 from newrelic.api.application import application_instance as __application
 from newrelic.api.application import application_settings as __application_settings
 from newrelic.api.application import register_application as __register_application
-from newrelic.api.log import NewRelicContextFormatter as __NewRelicContextFormatter
-from newrelic.api.time_trace import add_custom_span_attribute as __add_custom_span_attribute
-from newrelic.api.time_trace import current_trace as __current_trace
-from newrelic.api.time_trace import get_linking_metadata as __get_linking_metadata
-from newrelic.api.time_trace import notice_error as __notice_error
-from newrelic.api.transaction import accept_distributed_trace_headers as __accept_distributed_trace_headers
-from newrelic.api.transaction import add_custom_attribute as __add_custom_attribute
-from newrelic.api.transaction import add_custom_attributes as __add_custom_attributes
-from newrelic.api.transaction import add_framework_info as __add_framework_info
-from newrelic.api.transaction import capture_request_params as __capture_request_params
-from newrelic.api.transaction import current_span_id as __current_span_id
-from newrelic.api.transaction import current_trace_id as __current_trace_id
-from newrelic.api.transaction import current_transaction as __current_transaction
-from newrelic.api.transaction import disable_browser_autorum as __disable_browser_autorum
-from newrelic.api.transaction import end_of_transaction as __end_of_transaction
-from newrelic.api.transaction import get_browser_timing_header as __get_browser_timing_header
-from newrelic.api.transaction import ignore_transaction as __ignore_transaction
-from newrelic.api.transaction import insert_distributed_trace_headers as __insert_distributed_trace_headers
-from newrelic.api.transaction import record_custom_event as __record_custom_event
-from newrelic.api.transaction import record_custom_metric as __record_custom_metric
-from newrelic.api.transaction import record_custom_metrics as __record_custom_metrics
-from newrelic.api.transaction import record_log_event as __record_log_event
-from newrelic.api.transaction import record_ml_event as __record_ml_event
-from newrelic.api.transaction import set_background_task as __set_background_task
-from newrelic.api.transaction import set_transaction_name as __set_transaction_name
-from newrelic.api.transaction import suppress_apdex_metric as __suppress_apdex_metric
-from newrelic.api.transaction import suppress_transaction_trace as __suppress_transaction_trace
-from newrelic.api.wsgi_application import WSGIApplicationWrapper as __WSGIApplicationWrapper
-from newrelic.api.wsgi_application import wrap_wsgi_application as __wrap_wsgi_application
-from newrelic.api.wsgi_application import wsgi_application as __wsgi_application
-from newrelic.config import extra_settings as __extra_settings
-from newrelic.config import initialize as __initialize
-from newrelic.core.agent import register_data_source as __register_data_source
-from newrelic.core.agent import shutdown_agent as __shutdown_agent
-from newrelic.core.config import global_settings as __global_settings
-from newrelic.samplers.decorators import data_source_factory as __data_source_factory
-from newrelic.samplers.decorators import data_source_generator as __data_source_generator
-
-try:
-    from newrelic.api.asgi_application import ASGIApplicationWrapper as __ASGIApplicationWrapper
-    from newrelic.api.asgi_application import asgi_application as __asgi_application
-    from newrelic.api.asgi_application import wrap_asgi_application as __wrap_asgi_application
-except SyntaxError:
-
-    def __asgi_application(*args, **kwargs):
-        pass
-
-    __ASGIApplicationWrapper = __asgi_application
-    __wrap_asgi_application = __asgi_application
-
+from newrelic.api.asgi_application import ASGIApplicationWrapper as __ASGIApplicationWrapper
+from newrelic.api.asgi_application import asgi_application as __asgi_application
+from newrelic.api.asgi_application import wrap_asgi_application as __wrap_asgi_application
 from newrelic.api.background_task import BackgroundTask as __BackgroundTask
 from newrelic.api.background_task import BackgroundTaskWrapper as __BackgroundTaskWrapper
 from newrelic.api.background_task import background_task as __background_task
@@ -96,6 +49,7 @@ def __asgi_application(*args, **kwargs):
 from newrelic.api.html_insertion import insert_html_snippet as __insert_html_snippet
 from newrelic.api.html_insertion import verify_body_exists as __verify_body_exists
 from newrelic.api.llm_custom_attributes import WithLlmCustomAttributes as __WithLlmCustomAttributes
+from newrelic.api.log import NewRelicContextFormatter as __NewRelicContextFormatter
 from newrelic.api.message_trace import MessageTrace as __MessageTrace
 from newrelic.api.message_trace import MessageTraceWrapper as __MessageTraceWrapper
 from newrelic.api.message_trace import message_trace as __message_trace
@@ -112,7 +66,33 @@ def __asgi_application(*args, **kwargs):
 from newrelic.api.profile_trace import wrap_profile_trace as __wrap_profile_trace
 from newrelic.api.settings import set_error_group_callback as __set_error_group_callback
 from newrelic.api.supportability import wrap_api_call as __wrap_api_call
+from newrelic.api.time_trace import add_custom_span_attribute as __add_custom_span_attribute
+from newrelic.api.time_trace import current_trace as __current_trace
+from newrelic.api.time_trace import get_linking_metadata as __get_linking_metadata
+from newrelic.api.time_trace import notice_error as __notice_error
+from newrelic.api.transaction import accept_distributed_trace_headers as __accept_distributed_trace_headers
+from newrelic.api.transaction import add_custom_attribute as __add_custom_attribute
+from newrelic.api.transaction import add_custom_attributes as __add_custom_attributes
+from newrelic.api.transaction import add_framework_info as __add_framework_info
+from newrelic.api.transaction import capture_request_params as __capture_request_params
+from newrelic.api.transaction import current_span_id as __current_span_id
+from newrelic.api.transaction import current_trace_id as __current_trace_id
+from newrelic.api.transaction import current_transaction as __current_transaction
+from newrelic.api.transaction import disable_browser_autorum as __disable_browser_autorum
+from newrelic.api.transaction import end_of_transaction as __end_of_transaction
+from newrelic.api.transaction import get_browser_timing_header as __get_browser_timing_header
+from newrelic.api.transaction import ignore_transaction as __ignore_transaction
+from newrelic.api.transaction import insert_distributed_trace_headers as __insert_distributed_trace_headers
+from newrelic.api.transaction import record_custom_event as __record_custom_event
+from newrelic.api.transaction import record_custom_metric as __record_custom_metric
+from newrelic.api.transaction import record_custom_metrics as __record_custom_metrics
+from newrelic.api.transaction import record_log_event as __record_log_event
+from newrelic.api.transaction import record_ml_event as __record_ml_event
+from newrelic.api.transaction import set_background_task as __set_background_task
+from newrelic.api.transaction import set_transaction_name as __set_transaction_name
 from newrelic.api.transaction import set_user_id as __set_user_id
+from newrelic.api.transaction import suppress_apdex_metric as __suppress_apdex_metric
+from newrelic.api.transaction import suppress_transaction_trace as __suppress_transaction_trace
 from newrelic.api.transaction_name import TransactionNameWrapper as __TransactionNameWrapper
 from newrelic.api.transaction_name import transaction_name as __transaction_name
 from newrelic.api.transaction_name import wrap_transaction_name as __wrap_transaction_name
@@ -120,6 +100,9 @@ def __asgi_application(*args, **kwargs):
 from newrelic.api.web_transaction import WebTransactionWrapper as __WebTransactionWrapper
 from newrelic.api.web_transaction import web_transaction as __web_transaction
 from newrelic.api.web_transaction import wrap_web_transaction as __wrap_web_transaction
+from newrelic.api.wsgi_application import WSGIApplicationWrapper as __WSGIApplicationWrapper
+from newrelic.api.wsgi_application import wrap_wsgi_application as __wrap_wsgi_application
+from newrelic.api.wsgi_application import wsgi_application as __wsgi_application
 from newrelic.common.object_names import callable_name as __callable_name
 from newrelic.common.object_wrapper import CallableObjectProxy as __CallableObjectProxy
 from newrelic.common.object_wrapper import FunctionWrapper as __FunctionWrapper
@@ -143,6 +126,13 @@ def __asgi_application(*args, **kwargs):
 from newrelic.common.object_wrapper import wrap_out_function as __wrap_out_function
 from newrelic.common.object_wrapper import wrap_post_function as __wrap_post_function
 from newrelic.common.object_wrapper import wrap_pre_function as __wrap_pre_function
+from newrelic.config import extra_settings as __extra_settings
+from newrelic.config import initialize as __initialize
+from newrelic.core.agent import register_data_source as __register_data_source
+from newrelic.core.agent import shutdown_agent as __shutdown_agent
+from newrelic.core.config import global_settings as __global_settings
+from newrelic.samplers.decorators import data_source_factory as __data_source_factory
+from newrelic.samplers.decorators import data_source_generator as __data_source_generator
 
 # EXPERIMENTAL - Generator traces are currently experimental and may not
 # exist in this form in future versions of the agent.
diff --git a/newrelic/common/_monotonic.c b/newrelic/common/_monotonic.c
deleted file mode 100644
index 95f28f1a05..0000000000
--- a/newrelic/common/_monotonic.c
+++ /dev/null
@@ -1,155 +0,0 @@
-/*
- * Copyright 2010 New Relic, Inc.
- *
- * Licensed under the Apache License, Version 2.0 (the "License");
- * you may not use this file except in compliance with the License.
- * You may obtain a copy of the License at
- *
- *      http://www.apache.org/licenses/LICENSE-2.0
- *
- * Unless required by applicable law or agreed to in writing, software
- * distributed under the License is distributed on an "AS IS" BASIS,
- * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
- * See the License for the specific language governing permissions and
- * limitations under the License.
- */
-
-/*
- * This file is a modified back port of the monotonic() function from
- * Python 3.3. The original code was released under the Python Software
- * Foundation License Version 2.
- */
-
-#include <Python.h>
-
-#include <time.h>
-
-#if defined(__APPLE__)
-#include <mach/mach.h>
-#include <mach/mach_time.h>
-#endif
-
-#ifndef PyVarObject_HEAD_INIT
-#define PyVarObject_HEAD_INIT(type, size) PyObject_HEAD_INIT(type) size,
-#endif
-
-/* ------------------------------------------------------------------------- */
-
-static PyObject *monotonic(PyObject *self, PyObject *args)
-{
-#if defined(MS_WINDOWS)
-    static ULONGLONG (*GetTickCount64) (void) = NULL;
-    static ULONGLONG (CALLBACK *Py_GetTickCount64)(void);
-    static int has_getickcount64 = -1;
-    double result;
-
-    if (has_getickcount64 == -1) {
-        /* GetTickCount64() was added to Windows Vista */
-        if (winver.dwMajorVersion >= 6) {
-            HINSTANCE hKernel32;
-            hKernel32 = GetModuleHandleW(L"KERNEL32");
-            *(FARPROC*)&Py_GetTickCount64 = GetProcAddress(hKernel32,
-                                                           "GetTickCount64");
-            has_getickcount64 = (Py_GetTickCount64 != NULL);
-        }
-        else
-            has_getickcount64 = 0;
-    }
-
-    if (has_getickcount64) {
-        ULONGLONG ticks;
-        ticks = Py_GetTickCount64();
-        result = (double)ticks * 1e-3;
-    }
-    else {
-        static DWORD last_ticks = 0;
-        static DWORD n_overflow = 0;
-        DWORD ticks;
-
-        ticks = GetTickCount();
-        if (ticks < last_ticks)
-            n_overflow++;
-        last_ticks = ticks;
-
-        result = ldexp(n_overflow, 32);
-        result += ticks;
-        result *= 1e-3;
-    }
-
-    return PyFloat_FromDouble(result);
-
-#elif defined(__APPLE__)
-    static mach_timebase_info_data_t timebase;
-    uint64_t time;
-    double secs;
-
-    if (timebase.denom == 0) {
-        /* According to the Technical Q&A QA1398, mach_timebase_info() cannot
-           fail: https://developer.apple.com/library/mac/#qa/qa1398/ */
-        (void)mach_timebase_info(&timebase);
-    }
-
-    time = mach_absolute_time();
-    secs = (double)time * timebase.numer / timebase.denom * 1e-9;
-
-    return PyFloat_FromDouble(secs);
-
-#elif (defined(CLOCK_HIGHRES) || defined(CLOCK_MONOTONIC))
-    struct timespec tp;
-#ifdef CLOCK_HIGHRES
-    const clockid_t clk_id = CLOCK_HIGHRES;
-#else
-    const clockid_t clk_id = CLOCK_MONOTONIC;
-#endif
-
-    if (clock_gettime(clk_id, &tp) != 0) {
-        PyErr_SetFromErrno(PyExc_OSError);
-        return NULL;
-    }
-
-    return PyFloat_FromDouble(tp.tv_sec + tp.tv_nsec * 1e-9);
-#else
-    PyErr_SetNone(PyExc_NotImplementedError);
-    return NULL;
-#endif
-}
-
-/* ------------------------------------------------------------------------- */
-
-static PyMethodDef monotonic_methods[] = {
-    { "monotonic",          (PyCFunction)monotonic, METH_NOARGS, 0 },
-    { NULL, NULL }
-};
-
-static struct PyModuleDef moduledef = {
-    PyModuleDef_HEAD_INIT,
-    "_monotonic",        /* m_name */
-    NULL,                /* m_doc */
-    -1,                  /* m_size */
-    monotonic_methods,   /* m_methods */
-    NULL,                /* m_reload */
-    NULL,                /* m_traverse */
-    NULL,                /* m_clear */
-    NULL,                /* m_free */
-};
-
-static PyObject *
-moduleinit(void)
-{
-    PyObject *module;
-
-    module = PyModule_Create(&moduledef);
-
-    if (module == NULL)
-        return NULL;
-
-    return module;
-}
-
-PyMODINIT_FUNC PyInit__monotonic(void)
-{
-    return moduleinit();
-}
-
-/* ------------------------------------------------------------------------- */
-
diff --git a/newrelic/common/package_version_utils.py b/newrelic/common/package_version_utils.py
index 5b2886505c..da40f0dffa 100644
--- a/newrelic/common/package_version_utils.py
+++ b/newrelic/common/package_version_utils.py
@@ -69,7 +69,7 @@ def int_or_str(value):
     return version
 
 
-@lru_cache()
+@lru_cache
 def _get_package_version(name):
     module = sys.modules.get(name, None)
     version = None
diff --git a/newrelic/common/stopwatch.py b/newrelic/common/stopwatch.py
index 2305dda7e6..7c2edee4a8 100644
--- a/newrelic/common/stopwatch.py
+++ b/newrelic/common/stopwatch.py
@@ -20,36 +20,8 @@
 
 import time
 
-try:
-    # Python 3.3 and later implements PEP 418. Use the
-    # performance counter it provides which is monotonically
-    # increasing.
-
-    default_timer = time.perf_counter
-    timer_implementation = "time.perf_counter()"
-
-except AttributeError:
-    try:
-        # Next try our own bundled back port of the monotonic()
-        # function. Python 3.3 does on Windows use a different
-        # clock for the performance counter, but the standard
-        # monotonic clock should suit our requirements okay.
-
-        from newrelic.common._monotonic import monotonic as default_timer
-
-        default_timer()
-        timer_implementation = "_monotonic.monotonic()"
-
-    except (ImportError, NotImplementedError, OSError):
-        # If neither of the above, fallback to using the default
-        # timer from the timeit module. This will use the best
-        # resolution clock available on a particular platform,
-        # albeit that it isn't monotonically increasing.
-
-        import timeit
-
-        default_timer = timeit.default_timer
-        timer_implementation = "timeit.default_timer()"
+default_timer = time.perf_counter
+timer_implementation = "time.perf_counter()"
 
 # A timer class which deals with remembering the start time based on
 # wall clock time and duration based on a monotonic clock where
diff --git a/pyproject.toml b/pyproject.toml
index cb213b947c..810fdacf99 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -105,11 +105,10 @@ git_describe_command = 'git describe --dirty --tags --long --match "*.*.*"'
 [tool.ruff]
 output-format = "grouped"
 line-length = 120
-target-version = "py37"
+target-version = "py38"
 force-exclude = true  # Fixes issue with megalinter config preventing exclusion of files
 extend-exclude = [
     "newrelic/packages/",
-    "setup.py",
     "newrelic/core/infinite_tracing_*_pb2.py",
 ]
 namespace-packages = ["testing_support"]
@@ -201,7 +200,7 @@ ignore = [
     "PT012",  # pytest-raises-with-multiple-statements (too many to fix all at once)
     # Permanently disabled rules
     "PLC0415",  # import-outside-top-level (intentionally used frequently)
-    "UP006",  # non-pep585-annotation (not compatible with Python 3.7 or 3.8)
+    "UP006",  # non-pep585-annotation (not compatible with Python 3.8)
     "D203",  # incorrect-blank-line-before-class
     "D213",  # multi-line-summary-second-line
     "ARG001",  # unused-argument
@@ -225,6 +224,13 @@ ignore = [
 ]
 
 [tool.ruff.lint.per-file-ignores]
+"setup.py" = [
+    # Disabled rules in setup.py
+    # setup.py needs to not immediately crash on Python 2 to log error messages
+    "UP032",  # f-string (Python 3+ syntax)
+    "B904",  # raise-without-from-inside-except (Python 3+ syntax)
+    "E402",  # module-import-not-at-top-of-file (intentional)
+]
 "tests/*" = [
     # Disabled rules in tests
     "S",  # flake8-bandit (security checks are not necessary in tests)
diff --git a/setup.py b/setup.py
index a65e40d91e..2279145df3 100644
--- a/setup.py
+++ b/setup.py
@@ -15,15 +15,13 @@
 import os
 import sys
 
-from pathlib import Path
-
 python_version = sys.version_info[:2]
 
-if python_version >= (3, 7):
+if python_version >= (3, 8):
     pass
 else:
     error_msg = (
-        "The New Relic Python agent only supports Python 3.7+. We recommend upgrading to a newer version of Python."
+        "The New Relic Python agent only supports Python 3.8+. We recommend upgrading to a newer version of Python."
     )
 
     try:
@@ -35,14 +33,14 @@
             (3, 4): "4.20.0.120",
             (3, 5): "5.24.0.153",
             (3, 6): "7.16.0.178",
+            (3, 7): "10.17.0",
         }
         last_supported_version = last_supported_version_lookup.get(python_version, None)
 
         if last_supported_version:
-            python_version_str = "%s.%s" % (python_version[0], python_version[1])
-            error_msg += " The last agent version to support Python %s was v%s." % (
-                python_version_str,
-                last_supported_version,
+            python_version_str = "{}.{}".format(python_version[0], python_version[1])
+            error_msg += " The last agent version to support Python {} was v{}.".format(
+                python_version_str, last_supported_version
             )
     except Exception:
         pass
@@ -61,12 +59,9 @@
 from distutils.command.build_ext import build_ext
 from distutils.core import Extension
 from distutils.errors import CCompilerError, DistutilsExecError, DistutilsPlatformError
+from pathlib import Path
 
-
-if sys.platform == "win32":
-    build_ext_errors = (CCompilerError, DistutilsExecError, DistutilsPlatformError, IOError)
-else:
-    build_ext_errors = (CCompilerError, DistutilsExecError, DistutilsPlatformError)
+build_ext_errors = (CCompilerError, DistutilsExecError, DistutilsPlatformError, OSError)
 
 
 class BuildExtFailed(Exception):
@@ -78,27 +73,27 @@ def run(self):
         try:
             build_ext.run(self)
         except DistutilsPlatformError:
-            raise BuildExtFailed()
+            raise BuildExtFailed
 
     def build_extension(self, ext):
         try:
             build_ext.build_extension(self, ext)
         except build_ext_errors:
-            raise BuildExtFailed()
+            raise BuildExtFailed
 
 
-kwargs = dict(
-    name="newrelic",
-    setup_requires=["setuptools>=61.2", "setuptools_scm>=6.4,<10"],
-    license="Apache-2.0",
-)
+kwargs = {
+    "name": "newrelic",
+    "setup_requires": ["setuptools>=61.2", "setuptools_scm>=6.4,<10"],
+    "license": "Apache-2.0",
+}
 
 if not with_setuptools:
-    script_directory = os.path.dirname(__file__)
+    script_directory = Path(__file__).parent
     if not script_directory:
-        script_directory = os.getcwd()
+        script_directory = Path.cwd()
 
-    readme_file = os.path.join(script_directory, "README.md")
+    readme_file = script_directory / "README.md"
 
     kwargs["scripts"] = ["scripts/newrelic-admin"]
 
@@ -130,25 +125,22 @@ def build_extension(self, ext):
         "newrelic.samplers",
     ]
 
-    kwargs.update(dict(
-        python_requires=">=3.7",
-        zip_safe=False,
-        packages=packages,
-        package_data={
-            "newrelic": ["newrelic.ini", "version.txt", "packages/urllib3/LICENSE.txt", "common/cacert.pem", "scripts/azure-prebuild.sh"],
-        },
-    ))
-
-
-
-def with_librt():
-    try:
-        if sys.platform.startswith("linux"):
-            import ctypes.util
-
-            return ctypes.util.find_library("rt")
-    except Exception:
-        pass
+    kwargs.update(
+        {
+            "python_requires": ">=3.8",
+            "zip_safe": False,
+            "packages": packages,
+            "package_data": {
+                "newrelic": [
+                    "newrelic.ini",
+                    "version.txt",
+                    "packages/urllib3/LICENSE.txt",
+                    "common/cacert.pem",
+                    "scripts/azure-prebuild.sh",
+                ]
+            },
+        }
+    )
 
 
 def run_setup(with_extensions):
@@ -159,18 +151,11 @@ def _run_setup():
         kwargs_tmp = dict(kwargs)
 
         if with_extensions:
-            monotonic_libraries = []
-            if with_librt():
-                monotonic_libraries = ["rt"]
-
             kwargs_tmp["ext_modules"] = [
                 Extension("newrelic.packages.wrapt._wrappers", ["newrelic/packages/wrapt/_wrappers.c"]),
-                Extension(
-                    "newrelic.common._monotonic", ["newrelic/common/_monotonic.c"], libraries=monotonic_libraries
-                ),
                 Extension("newrelic.core._thread_utilization", ["newrelic/core/_thread_utilization.c"]),
             ]
-            kwargs_tmp["cmdclass"] = dict(build_ext=optional_build_ext)
+            kwargs_tmp["cmdclass"] = {"build_ext": optional_build_ext}
 
         setup(**kwargs_tmp)
 
diff --git a/tests/agent_features/test_attributes_in_action.py b/tests/agent_features/test_attributes_in_action.py
index 0b24a3100a..4d12e8b059 100644
--- a/tests/agent_features/test_attributes_in_action.py
+++ b/tests/agent_features/test_attributes_in_action.py
@@ -14,6 +14,7 @@
 
 import pytest
 import webtest
+from testing_support.asgi_testing import AsgiTest
 from testing_support.fixtures import (
     cat_enabled,
     dt_enabled,
@@ -21,6 +22,7 @@
     reset_core_stats_engine,
     validate_attributes,
 )
+from testing_support.sample_asgi_applications import normal_asgi_application
 from testing_support.validators.validate_browser_attributes import validate_browser_attributes
 from testing_support.validators.validate_error_event_attributes import validate_error_event_attributes
 from testing_support.validators.validate_error_event_attributes_outside_transaction import (
@@ -45,13 +47,6 @@
 from newrelic.api.wsgi_application import wsgi_application
 from newrelic.common.object_names import callable_name
 
-try:
-    from testing_support.asgi_testing import AsgiTest
-    from testing_support.sample_asgi_applications import normal_asgi_application
-except SyntaxError:
-    normal_asgi_application = None
-
-
 URL_PARAM = "some_key"
 URL_PARAM2 = "second_key"
 REQUEST_URL = f"/?{URL_PARAM}=someval&{URL_PARAM2}=anotherval"
@@ -160,12 +155,7 @@ def normal_wsgi_application(environ, start_response):
     return [output]
 
 
-application_params = [normal_wsgi_application]
-if normal_asgi_application:
-    application_params.append(normal_asgi_application)
-
-
-@pytest.fixture(scope="module", params=application_params)
+@pytest.fixture(scope="module", params=[normal_wsgi_application, normal_asgi_application])
 def normal_application(request):
     if request.param is normal_wsgi_application:
         return webtest.TestApp(normal_wsgi_application)
diff --git a/tests/framework_flask/conftest.py b/tests/framework_flask/conftest.py
index 872de5b53c..f2881d0c75 100644
--- a/tests/framework_flask/conftest.py
+++ b/tests/framework_flask/conftest.py
@@ -15,18 +15,11 @@
 import platform
 
 import pytest
-from flask import __version__ as flask_version  # required for python 3.7 in lieu of get_package_version_tuple
+from testing_support.fixtures import collector_agent_registration_fixture, collector_available_fixture
 
 from newrelic.common.package_version_utils import get_package_version_tuple
 
-try:
-    FLASK_VERSION = tuple(int(v) for v in flask_version.split("."))
-except:
-    # This does not work for Python 3.7 for v2.2.5
-    # This only works for flaskmaster
-    FLASK_VERSION = get_package_version_tuple("flask")
-
-from testing_support.fixtures import collector_agent_registration_fixture, collector_available_fixture
+FLASK_VERSION = get_package_version_tuple("flask")
 
 _default_settings = {
     "package_reporting.enabled": False,  # Turn off package reporting for testing as it causes slow downs.
diff --git a/tests/framework_starlette/test_application.py b/tests/framework_starlette/test_application.py
index 55f751e9a3..cd5668fcb8 100644
--- a/tests/framework_starlette/test_application.py
+++ b/tests/framework_starlette/test_application.py
@@ -120,7 +120,7 @@ def test_exception_in_middleware(target_application, app_name):
 
     # Starlette >=0.15 and <0.17 raises an exception group instead of reraising the ValueError
     # This only occurs on Python versions >=3.8
-    if sys.version_info[0:2] > (3, 7) and starlette_version >= (0, 15, 0) and starlette_version < (0, 17, 0):
+    if (0, 15, 0) <= starlette_version < (0, 17, 0):
         from anyio._backends._asyncio import ExceptionGroup
 
         exc_type = ExceptionGroup
diff --git a/tests/framework_starlette/test_bg_tasks.py b/tests/framework_starlette/test_bg_tasks.py
index 5c339e7a49..15b37eafb8 100644
--- a/tests/framework_starlette/test_bg_tasks.py
+++ b/tests/framework_starlette/test_bg_tasks.py
@@ -85,15 +85,9 @@ def _test():
         assert response.status == 200
 
     # The bug was fixed in version 0.21.0 but re-occured in 0.23.1.
-    # The bug was also not present on 0.20.1 to 0.23.1 if using Python3.7.
+    # The bug was also not present on 0.20.1 to 0.23.1 if using Python 3.7.
     # The bug was fixed again in version 0.29.0
-    BUG_COMPLETELY_FIXED = any(
-        (
-            (0, 21, 0) <= starlette_version < (0, 23, 1),
-            (0, 20, 1) <= starlette_version < (0, 23, 1) and sys.version_info[:2] > (3, 7),
-            starlette_version >= (0, 29, 0),
-        )
-    )
+    BUG_COMPLETELY_FIXED = any(((0, 20, 1) <= starlette_version < (0, 23, 1), starlette_version >= (0, 29, 0)))
     BUG_PARTIALLY_FIXED = any(
         ((0, 20, 1) <= starlette_version < (0, 21, 0), (0, 23, 1) <= starlette_version < (0, 29, 0))
     )
diff --git a/tox.ini b/tox.ini
index d40901288f..1a20c1243a 100644
--- a/tox.ini
+++ b/tox.ini
@@ -16,7 +16,7 @@
 ;           framework_aiohttp-aiohttp01: aiohttp<2
 ;           framework_aiohttp-aiohttp0202: aiohttp<2.3
 ; 3. Python version required. Uses the standard tox definitions. (https://tox.readthedocs.io/en/latest/config.html#tox-environments)
-;    Examples: py37,py38,py39,pypy310
+;    Examples: py38,py39,py310,py311,py312,py313,pypy310
 ; 4. Library and version (Optional). Used when testing multiple versions of the library, and may be omitted when only testing a single version.
 ;    Versions should be specified with 2 digits per version number, so <3 becomes 02 and <3.5 becomes 0304. latest and master are also acceptable versions.
 ;    Examples: uvicorn03, CherryPy0302, uvicornlatest
@@ -29,13 +29,13 @@
 ;    Examples: with_extensions, without_extensions
 ;       envlist =
 ;           python-agent_features-pypy310-without_extensions,
-;           python-agent_streaming-py37-{with,without}_extensions,
+;           python-agent_streaming-py312-{with,without}_extensions,
 ;
 ; Full Format:
 ;   services_required-tests_folder-python_version-library_and_version[optional]-with/without_c_extensions[optional]
 ;
 ; Full Examples:
-;   - memcached-datastore_bmemcached-py37-memcached030
+;   - memcached-datastore_bmemcached-py313-memcached030
 ;   - python-agent_unittests-py38-with_extensions
 ;   - python-adapter_gevent-py39
 
@@ -45,157 +45,150 @@ setupdir = {toxinidir}
 skip_missing_interpreters = false
 envlist =
     cassandra-datastore_cassandradriver-{py38,py39,py310,py311,py312,pypy310}-cassandralatest,
-    elasticsearchserver07-datastore_elasticsearch-{py37,py38,py39,py310,py311,py312,py313,pypy310}-elasticsearch07,
-    elasticsearchserver08-datastore_elasticsearch-{py37,py38,py39,py310,py311,py312,py313,pypy310}-elasticsearch08,
-    firestore-datastore_firestore-{py37,py38,py39,py310,py311,py312,py313},
+    elasticsearchserver07-datastore_elasticsearch-{py38,py39,py310,py311,py312,py313,pypy310}-elasticsearch07,
+    elasticsearchserver08-datastore_elasticsearch-{py38,py39,py310,py311,py312,py313,pypy310}-elasticsearch08,
+    firestore-datastore_firestore-{py38,py39,py310,py311,py312,py313},
     grpc-framework_grpc-{py39,py310,py311,py312,py313}-grpclatest,
     kafka-messagebroker_confluentkafka-py39-confluentkafka{0108,0107,0106},
-    kafka-messagebroker_confluentkafka-{py37,py38,py39,py310,py311,py312,py313}-confluentkafkalatest,
-    kafka-messagebroker_kafkapython-{py37,py38,py39,py310,py311,py312,py313,pypy310}-kafkapythonlatest,
+    kafka-messagebroker_confluentkafka-{py38,py39,py310,py311,py312,py313}-confluentkafkalatest,
+    kafka-messagebroker_kafkapython-{py38,py39,py310,py311,py312,py313,pypy310}-kafkapythonlatest,
     kafka-messagebroker_kafkapython-{py38,py39,py310,py311,py312,py313,pypy310}-kafkapythonnglatest,
     memcached-datastore_aiomcache-{py38,py39,py310,py311,py312,py313},
-    memcached-datastore_bmemcached-{py37,py38,py39,py310,py311,py312,py313},
-    memcached-datastore_memcache-{py37,py38,py39,py310,py311,py312,py313,pypy310}-memcached01,
-    memcached-datastore_pylibmc-py37,
-    memcached-datastore_pymemcache-{py37,py38,py39,py310,py311,py312,py313,pypy310},
-    mongodb8-datastore_motor-{py37,py38,py39,py310,py311,py312,py313}-motorlatest,
-    mongodb3-datastore_pymongo-{py37,py38,py39,py310,py311,py312}-pymongo03,
-    mongodb8-datastore_pymongo-{py37,py38,py39,py310,py311,py312,py313,pypy310}-pymongo04,
+    memcached-datastore_bmemcached-{py38,py39,py310,py311,py312,py313},
+    memcached-datastore_memcache-{py38,py39,py310,py311,py312,py313,pypy310}-memcached01,
+    memcached-datastore_pylibmc-{py38,py39,py310,py311},
+    memcached-datastore_pymemcache-{py38,py39,py310,py311,py312,py313,pypy310},
+    mongodb8-datastore_motor-{py38,py39,py310,py311,py312,py313}-motorlatest,
+    mongodb3-datastore_pymongo-{py38,py39,py310,py311,py312}-pymongo03,
+    mongodb8-datastore_pymongo-{py38,py39,py310,py311,py312,py313,pypy310}-pymongo04,
     ; aiomysql tests on PyPy disabled for now due to issues building cryptography
-    mysql-datastore_aiomysql-{py37,py38,py39,py310,py311,py312,py313},
+    mysql-datastore_aiomysql-{py38,py39,py310,py311,py312,py313},
     mssql-datastore_pymssql-pymssqllatest-{py39,py310,py311,py312,py313},
-    mssql-datastore_pymssql-pymssql020301-{py37,py38},
-    mysql-datastore_mysql-mysqllatest-{py37,py38,py39,py310,py311,py312,py313},
+    mssql-datastore_pymssql-pymssql020301-py38,
+    mysql-datastore_mysql-mysqllatest-{py38,py39,py310,py311,py312,py313},
     mysql-datastore_mysqldb-{py38,py39,py310,py311,py312,py313},
     ; pymysql tests on PyPy disabled for now due to issues building cryptography
-    mysql-datastore_pymysql-{py37,py38,py39,py310,py311,py312,py313},
+    mysql-datastore_pymysql-{py38,py39,py310,py311,py312,py313},
     oracledb-datastore_oracledb-{py39,py310,py311,py312,py313}-oracledblatest,
     oracledb-datastore_oracledb-{py39,py313}-oracledb02,
     oracledb-datastore_oracledb-{py39,py312}-oracledb01,
-    nginx-external_httpx-{py37,py38,py39,py310,py311,py312,py313},
-    postgres16-datastore_asyncpg-{py37,py38,py39,py310,py311,py312,py313},
+    nginx-external_httpx-{py38,py39,py310,py311,py312,py313},
+    postgres16-datastore_asyncpg-{py38,py39,py310,py311,py312,py313},
     postgres16-datastore_psycopg-{py38,py39,py310,py311,py312,py313,pypy310}-psycopglatest,
     postgres16-datastore_psycopg-py312-psycopg_{purepython,binary,compiled}0301,
-    postgres16-datastore_psycopg2-{py37,py38,py39,py310,py311,py312}-psycopg2latest,
-    postgres16-datastore_psycopg2cffi-{py37,py38,py39,py310,py311,py312}-psycopg2cffilatest,
-    postgres16-datastore_pyodbc-{py37,py38,py39,py310,py311,py312,py313}-pyodbclatest,
-    postgres9-datastore_postgresql-{py37,py38,py39,py310,py311,py312,py313},
-    python-adapter_asgiref-{py37,py38,py39,py310,py311,py312,py313,pypy310}-asgireflatest,
+    postgres16-datastore_psycopg2-{py38,py39,py310,py311,py312}-psycopg2latest,
+    postgres16-datastore_psycopg2cffi-{py38,py39,py310,py311,py312}-psycopg2cffilatest,
+    postgres16-datastore_pyodbc-{py38,py39,py310,py311,py312,py313}-pyodbclatest,
+    postgres9-datastore_postgresql-{py38,py39,py310,py311,py312,py313},
+    python-adapter_asgiref-{py38,py39,py310,py311,py312,py313,pypy310}-asgireflatest,
     python-adapter_asgiref-py310-asgiref{0303,0304,0305,0306,0307},
-    python-adapter_cheroot-{py37,py38,py39,py310,py311,py312,py313},
-    python-adapter_daphne-{py37,py38,py39,py310,py311,py312,py313}-daphnelatest,
-    python-adapter_gevent-{py37,py38,py310,py311,py312,py313},
-    python-adapter_gunicorn-{py37,py38,py39,py310,py311,py312,py313}-aiohttp03-gunicornlatest,
+    python-adapter_cheroot-{py38,py39,py310,py311,py312,py313},
+    python-adapter_daphne-{py38,py39,py310,py311,py312,py313}-daphnelatest,
+    python-adapter_gevent-{py38,py310,py311,py312,py313},
+    python-adapter_gunicorn-{py38,py39,py310,py311,py312,py313}-aiohttp03-gunicornlatest,
     python-adapter_hypercorn-{py38,py39,py310,py311,py312,py313}-hypercornlatest,
     python-adapter_hypercorn-py38-hypercorn{0010,0011,0012,0013},
     ; mcp tests on PyPy disabled for now due to issues building cryptography
     python-adapter_mcp-{py310,py311,py312,py313},
-    python-adapter_uvicorn-{py37,py38,py39,py310,py311,py312,py313}-uvicornlatest,
+    python-adapter_uvicorn-{py38,py39,py310,py311,py312,py313}-uvicornlatest,
     python-adapter_uvicorn-py38-uvicorn014,
-    python-adapter_waitress-{py37,py38,py39,py310,py311,py312,py313}-waitresslatest,
-    python-agent_features-{py37,py38,py39,py310,py311,py312,py313}-{with,without}_extensions,
+    python-adapter_waitress-{py38,py39,py310,py311,py312,py313}-waitresslatest,
+    python-agent_features-{py38,py39,py310,py311,py312,py313}-{with,without}_extensions,
     python-agent_features-pypy310-without_extensions,
-    python-agent_streaming-{py37,py38,py39,py310,py311,py312,py313}-protobuf06-{with,without}_extensions,
+    python-agent_streaming-{py38,py39,py310,py311,py312,py313}-protobuf06-{with,without}_extensions,
     python-agent_streaming-py39-protobuf{03,0319,04,05}-{with,without}_extensions,
-    python-agent_unittests-{py37,py38,py39,py310,py311,py312,py313}-{with,without}_extensions,
+    python-agent_unittests-{py38,py39,py310,py311,py312,py313}-{with,without}_extensions,
     python-agent_unittests-pypy310-without_extensions,
-    python-application_celery-{py37,py38,py39,py310,py311,py312,py313,pypy310}-celerylatest,
+    python-application_celery-{py38,py39,py310,py311,py312,py313,pypy310}-celerylatest,
     python-application_celery-py311-celery{0504,0503,0502},
-    python-component_djangorestframework-{py37,py38,py39,py310,py311,py312,py313}-djangorestframeworklatest,
+    python-component_djangorestframework-{py38,py39,py310,py311,py312,py313}-djangorestframeworklatest,
     python-component_flask_rest-{py38,py39,py310,py311,py312,py313,pypy310}-flaskrestxlatest,
-    python-component_flask_rest-py37-flaskrestx110,
-    python-component_graphqlserver-{py37,py38,py39,py310,py311,py312},
+    python-component_graphqlserver-{py38,py39,py310,py311,py312},
     ;; Tests need to be updated to support newer graphql-server/sanic versions
     ; python-component_graphqlserver-py313,
-    python-component_tastypie-{py37,py38,py39,py310,py311,py312,py313,pypy310}-tastypielatest,
-    python-coroutines_asyncio-{py37,py38,py39,py310,py311,py312,py313,pypy310},
-    python-cross_agent-{py37,py38,py39,py310,py311,py312,py313}-{with,without}_extensions,
-    python-datastore_sqlite-{py37,py38,py39,py310,py311,py312,py313,pypy310},
+    python-component_tastypie-{py38,py39,py310,py311,py312,py313,pypy310}-tastypielatest,
+    python-coroutines_asyncio-{py38,py39,py310,py311,py312,py313,pypy310},
+    python-cross_agent-{py38,py39,py310,py311,py312,py313}-{with,without}_extensions,
+    python-datastore_sqlite-{py38,py39,py310,py311,py312,py313,pypy310},
     python-external_aiobotocore-{py38,py39,py310,py311,py312,py313}-aiobotocorelatest,
     python-external_botocore-{py38,py39,py310,py311,py312,py313}-botocorelatest,
     python-external_botocore-{py311}-botocorelatest-langchain,
     python-external_botocore-py310-botocore0125,
     python-external_botocore-py311-botocore0128,
-    python-external_feedparser-{py37,py38,py39,py310,py311,py312,py313}-feedparser06,
-    python-external_http-{py37,py38,py39,py310,py311,py312,py313},
-    python-external_httplib-{py37,py38,py39,py310,py311,py312,py313,pypy310},
-    python-external_httplib2-{py37,py38,py39,py310,py311,py312,py313,pypy310},
+    python-external_feedparser-{py38,py39,py310,py311,py312,py313}-feedparser06,
+    python-external_http-{py38,py39,py310,py311,py312,py313},
+    python-external_httplib-{py38,py39,py310,py311,py312,py313,pypy310},
+    python-external_httplib2-{py38,py39,py310,py311,py312,py313,pypy310},
     python-external_pyzeebe-{py39,py310,py311,py312,pypy310},
-    python-external_requests-{py37,py38,py39,py310,py311,py312,py313,pypy310},
-    python-external_urllib3-{py37,py38,py39,py310,py311,py312,py313,pypy310}-urllib3latest,
-    python-external_urllib3-{py37,py312,py313,pypy310}-urllib30126,
-    python-framework_aiohttp-{py37,py38,py39,py310,py311,py312,py313,pypy310}-aiohttp03,
-    python-framework_ariadne-{py37,py38,py39,py310,py311,py312,py313}-ariadnelatest,
-    python-framework_ariadne-py37-ariadne{0011,0012,0013},
+    python-external_requests-{py38,py39,py310,py311,py312,py313,pypy310},
+    python-external_urllib3-{py38,py39,py310,py311,py312,py313,pypy310}-urllib3latest,
+    python-external_urllib3-{py312,py313,pypy310}-urllib30126,
+    python-framework_aiohttp-{py38,py39,py310,py311,py312,py313,pypy310}-aiohttp03,
+    python-framework_ariadne-{py38,py39,py310,py311,py312,py313}-ariadnelatest,
     python-framework_azurefunctions-{py39,py310,py311,py312},
-    python-framework_bottle-{py37,py38,py39,py310,py311,py312,py313,pypy310}-bottle0012,
-    python-framework_cherrypy-{py37,py38,py39,py310,py311,py312,py313,pypy310}-CherryPylatest,
-    python-framework_django-{py37,py38,py39,py310,py311,py312,py313}-Djangolatest,
-    python-framework_django-{py39}-Django{0202,0300,0301,0302,0401},
+    python-framework_bottle-{py38,py39,py310,py311,py312,py313,pypy310}-bottle0012,
+    python-framework_cherrypy-{py38,py39,py310,py311,py312,py313,pypy310}-CherryPylatest,
+    python-framework_django-{py38,py39,py310,py311,py312,py313}-Djangolatest,
+    python-framework_django-py39-Django{0202,0300,0301,0302,0401},
     python-framework_falcon-{py39,py310,py311,py312,py313,pypy310}-falconlatest,
-    python-framework_falcon-{py37,py38}-falcon0410,
+    python-framework_falcon-py38-falcon0410,
     python-framework_falcon-{py39,py310,py311,py312,py313,pypy310}-falconmaster,
-    python-framework_fastapi-{py37,py38,py39,py310,py311,py312,py313},
-    python-framework_flask-py37-flask020205,
+    python-framework_fastapi-{py38,py39,py310,py311,py312,py313},
     python-framework_flask-{py38,py39,py310,py311,py312,pypy310}-flask02,
-    ; python-framework_flask-py38-flaskmaster fails, even with Flask-Compress<1.16 and coverage==7.61 for py37,py38
+    ; python-framework_flask-py38-flaskmaster fails, even with Flask-Compress<1.16 and coverage==7.61 for py38
     python-framework_flask-py38-flasklatest,
     ; flaskmaster tests disabled until they can be fixed
     python-framework_flask-{py39,py310,py311,py312,py313,pypy310}-flask{latest},
-    python-framework_graphene-{py37,py38,py39,py310,py311,py312,py313}-graphenelatest,
-    python-component_graphenedjango-{py37,py38,py39,py310,py311,py312,py313}-graphenedjangolatest,
-    python-framework_graphql-{py37,py38,py39,py310,py311,py312,py313,pypy310}-graphql03,
-    python-framework_graphql-{py37,py38,py39,py310,py311,py312,py313,pypy310}-graphql{latest},
-    python-framework_graphql-py37-graphql{0301,0302},
-    python-framework_pyramid-{py37,py38,py39,py310,py311,py312,py313,pypy310}-Pyramidlatest,
-    python-framework_pyramid-{py37,py38,py39,py310,py311,py312,py313,pypy310}-Pyramid0110-cornice,
-    python-framework_sanic-{py37,py38}-sanic2406,
+    python-framework_graphene-{py38,py39,py310,py311,py312,py313}-graphenelatest,
+    python-component_graphenedjango-{py38,py39,py310,py311,py312,py313}-graphenedjangolatest,
+    python-framework_graphql-{py38,py39,py310,py311,py312,py313,pypy310}-graphql03,
+    python-framework_graphql-{py38,py39,py310,py311,py312,py313,pypy310}-graphqllatest,
+    python-framework_pyramid-{py38,py39,py310,py311,py312,py313,pypy310}-Pyramidlatest,
+    python-framework_pyramid-{py38,py39,py310,py311,py312,py313,pypy310}-Pyramid0110-cornice,
+    python-framework_sanic-{py38}-sanic2406,
     python-framework_sanic-{py39,py310,py311,py312,py313,pypy310}-saniclatest,
     python-framework_sanic-{py38,pypy310}-sanic2290,
     python-framework_starlette-{py310,pypy310}-starlette{0014,0015,0019,0028},
-    python-framework_starlette-{py37,py38,py39,py310,py311,py312,py313,pypy310}-starlettelatest,
-    python-framework_starlette-{py37,py38}-starlette002001,
+    python-framework_starlette-{py38,py39,py310,py311,py312,py313,pypy310}-starlettelatest,
+    python-framework_starlette-{py38}-starlette002001,
     python-framework_strawberry-{py38,py39,py310,py311,py312}-strawberry02352,
-    python-framework_strawberry-{py37,py38,py39,py310,py311,py312,py313}-strawberrylatest,
+    python-framework_strawberry-{py38,py39,py310,py311,py312,py313}-strawberrylatest,
     python-framework_tornado-{py38,py39,py310,py311,py312,py313}-tornadolatest,
     python-framework_tornado-{py310,py311,py312,py313}-tornadomaster,
-    python-logger_logging-{py37,py38,py39,py310,py311,py312,py313,pypy310},
-    python-logger_loguru-{py37,py38,py39,py310,py311,py312,py313,pypy310}-logurulatest,
-    python-logger_structlog-{py37,py38,py39,py310,py311,py312,py313,pypy310}-structloglatest,
+    python-logger_logging-{py38,py39,py310,py311,py312,py313,pypy310},
+    python-logger_loguru-{py38,py39,py310,py311,py312,py313,pypy310}-logurulatest,
+    python-logger_structlog-{py38,py39,py310,py311,py312,py313,pypy310}-structloglatest,
     python-mlmodel_gemini-{py39,py310,py311,py312,py313},
     python-mlmodel_langchain-{py39,py310,py311,py312},
     ;; Package not ready for Python 3.13 (uses an older version of numpy)
     ; python-mlmodel_langchain-py313,
-    python-mlmodel_openai-openai0-{py37,py38,py39,py310,py311,py312},
+    python-mlmodel_openai-openai0-{py38,py39,py310,py311,py312},
     python-mlmodel_openai-openai107-py312,
-    python-mlmodel_openai-openailatest-{py37,py38,py39,py310,py311,py312,py313},
-    python-mlmodel_sklearn-{py37}-scikitlearn0101,
+    python-mlmodel_openai-openailatest-{py38,py39,py310,py311,py312,py313},
     python-mlmodel_sklearn-{py38,py39,py310,py311,py312,py313}-scikitlearnlatest,
-    python-template_genshi-{py37,py38,py39,py310,py311,py312,py313}-genshilatest,
+    python-template_genshi-{py38,py39,py310,py311,py312,py313}-genshilatest,
     python-template_jinja2-{py38,py39,py310,py311,py312,py313}-jinja2latest,
-    python-template_jinja2-py37-jinja2030103,
-    python-template_mako-{py37,py38,py39,py310,py311,py312,py313},
-    rabbitmq-messagebroker_pika-{py37,py38,py39,py310,py311,py312,py313,pypy310}-pikalatest,
+    python-template_mako-{py38,py39,py310,py311,py312,py313},
+    rabbitmq-messagebroker_pika-{py38,py39,py310,py311,py312,py313,pypy310}-pikalatest,
     rabbitmq-messagebroker_kombu-{py38,py39,py310,py311,py312,py313,pypy310}-kombulatest,
     rabbitmq-messagebroker_kombu-{py38,py39,py310,pypy310}-kombu050204,
-    redis-datastore_redis-{py37,py38,py39,py310,py311,pypy310}-redis04,
+    redis-datastore_redis-{py38,py39,py310,py311,pypy310}-redis04,
     redis-datastore_redis-{py38,py39,py310,py311,py312,pypy310}-redis05,
     redis-datastore_redis-{py38,py39,py310,py311,py312,py313,pypy310}-redislatest,
-    rediscluster-datastore_rediscluster-{py37,py312,py313,pypy310}-redislatest,
+    rediscluster-datastore_rediscluster-{py312,py313,pypy310}-redislatest,
     valkey-datastore_valkey-{py38,py39,py310,py311,py312,py313,pypy310}-valkeylatest,
-    solr-datastore_pysolr-{py37,py38,py39,py310,py311,py312,py313,pypy310},
+    solr-datastore_pysolr-{py38,py39,py310,py311,py312,py313,pypy310},
 
 [testenv]
 deps =
     # Base Dependencies
     {py39,py310,py311,py312,py313,pypy310}: pytest==8.4.1
     py38: pytest==8.3.5
-    py37: pytest==7.4.4
     iniconfig
     coverage
     {py39,py310,py311,py312,py313,pypy310}: WebTest==3.0.6
+    py38: WebTest==3.0.1
     py313: legacy-cgi==2.6.1  # cgi was removed from the stdlib in 3.13, and is required for WebTest
-    {py37,py38}: WebTest==3.0.1
 
     # Test Suite Dependencies
     adapter_asgiref-asgireflatest: asgiref
@@ -238,14 +231,12 @@ deps =
     application_celery-celery0504: celery[pytest]<5.5
     application_celery-celery0503: celery[pytest]<5.4
     application_celery-celery0502: celery[pytest]<5.3
-    application_celery-{py37,pypy310}: importlib-metadata<5.0
+    application_celery-pypy310: importlib-metadata<5.0
     mlmodel_sklearn: pandas
     mlmodel_sklearn: protobuf
     mlmodel_sklearn: numpy
     mlmodel_sklearn-scikitlearnlatest: scikit-learn
     mlmodel_sklearn-scikitlearnlatest: scipy
-    mlmodel_sklearn-scikitlearn0101: scikit-learn<1.1
-    mlmodel_sklearn-scikitlearn0101: scipy<1.11.0
     component_djangorestframework-djangorestframeworklatest: Django
     component_djangorestframework-djangorestframeworklatest: djangorestframework
     component_flask_rest: flask-restful
@@ -253,11 +244,6 @@ deps =
     component_flask_rest: itsdangerous
     component_flask_rest-flaskrestxlatest: flask
     component_flask_rest-flaskrestxlatest: flask-restx
-    ; flask-restx only supports Flask v3 after flask-restx v1.3.0
-    component_flask_rest-flaskrestx110: Flask<3.0
-    component_flask_rest-flaskrestx110: flask-restx<1.2
-    component_flask_rest-flaskrestx051: Flask<3.0
-    component_flask_rest-flaskrestx051: flask-restx<1.0
     component_graphqlserver: graphql-server[sanic,flask]==3.0.0b5
     component_graphqlserver: sanic>20
     component_graphqlserver: Flask
@@ -266,7 +252,7 @@ deps =
     component_tastypie-tastypielatest: django-tastypie
     component_tastypie-tastypielatest: django<4.1
     component_tastypie-tastypielatest: asgiref<3.7.1  # asgiref==3.7.1 only suppport Python 3.10+
-    coroutines_asyncio-{py37,py38,py39,py310,py311,py312,py313}: uvloop
+    coroutines_asyncio-{py38,py39,py310,py311,py312,py313}: uvloop
     cross_agent: requests
     datastore_asyncpg: asyncpg
     datastore_aiomcache: aiomcache
@@ -340,9 +326,6 @@ deps =
     framework_aiohttp-aiohttp03: aiohttp<4
     framework_aiohttp-aiohttp030900rc0: aiohttp==3.9.0rc0
     framework_ariadne-ariadnelatest: ariadne
-    framework_ariadne-ariadne0011: ariadne<0.12
-    framework_ariadne-ariadne0012: ariadne<0.13
-    framework_ariadne-ariadne0013: ariadne<0.14
     framework_azurefunctions: azure-functions
     framework_azurefunctions: requests
     framework_bottle-bottle0012: bottle<0.13.0
@@ -365,8 +348,6 @@ deps =
     framework_flask: Flask-Compress
     framework_flask-flask02: flask[async]<3
     framework_flask-flask02: jinja2<3.1.3
-    framework_flask-flask020205: jinja2<3.1.3
-    framework_flask-flask020205: flask[async]<2.3
     framework_flask-flasklatest: markupsafe
     framework_flask-flasklatest: jinja2
     framework_flask-flasklatest: flask[async]
@@ -375,11 +356,8 @@ deps =
     framework_flask-flaskmaster: asgiref
     framework_graphene-graphenelatest: graphene
     component_graphenedjango-graphenedjangolatest: graphene-django
-    framework_graphql-graphqllatest: graphql-core
     framework_graphql-graphql03: graphql-core<4
-    framework_graphql-graphql0301: graphql-core<3.2
-    framework_graphql-graphql0302: graphql-core<3.3
-    framework_graphql-graphqlmaster: https://github.com/graphql-python/graphql-core/archive/main.zip
+    framework_graphql-graphqllatest: graphql-core
     framework_grpc-grpclatest: protobuf
     framework_grpc-grpclatest: grpcio
     framework_grpc-grpclatest: grpcio-tools
@@ -446,7 +424,6 @@ deps =
     messagebroker_kafkapython-kafkapythonlatest: kafka-python<2.1
     template_genshi-genshilatest: genshi
     template_jinja2-jinja2latest: Jinja2
-    template_jinja2-jinja2030103: Jinja2<3.1.4
     template_mako: mako
 
 setenv =