diff --git a/ChangeLog b/ChangeLog
index 5c587d8fc9..2f6fd29ee5 100644
--- a/ChangeLog
+++ b/ChangeLog
@@ -121,6 +121,10 @@ Release date: TBA
 
   Refs #2141
 
+* Remove deprecated ``is_sys_guard`` and ``is_typing_guard`` methods.
+
+  Refs #2153
+
 * Remove deprecated ``Ellipsis``, ``ExtSlice``, ``Index`` nodes.
 
   Refs #2152
diff --git a/astroid/nodes/node_classes.py b/astroid/nodes/node_classes.py
index 9df654c5f4..2c28c7bc35 100644
--- a/astroid/nodes/node_classes.py
+++ b/astroid/nodes/node_classes.py
@@ -9,7 +9,6 @@
 import abc
 import itertools
 import typing
-import warnings
 from collections.abc import Generator, Iterable, Iterator, Mapping
 from functools import cached_property, lru_cache
 from typing import (
@@ -2483,59 +2482,6 @@ def _get_yield_nodes_skip_lambdas(self):
         yield from self.test._get_yield_nodes_skip_lambdas()
         yield from super()._get_yield_nodes_skip_lambdas()
 
-    def is_sys_guard(self) -> bool:
-        """Return True if IF stmt is a sys.version_info guard.
-
-        >>> import astroid
-        >>> node = astroid.extract_node('''
-        import sys
-        if sys.version_info > (3, 8):
-            from typing import Literal
-        else:
-            from typing_extensions import Literal
-        ''')
-        >>> node.is_sys_guard()
-        True
-        """
-        warnings.warn(
-            "The 'is_sys_guard' function is deprecated and will be removed in astroid 3.0.0 "
-            "It has been moved to pylint and can be imported from 'pylint.checkers.utils' "
-            "starting with pylint 2.12",
-            DeprecationWarning,
-            stacklevel=2,
-        )
-        if isinstance(self.test, Compare):
-            value = self.test.left
-            if isinstance(value, Subscript):
-                value = value.value
-            if isinstance(value, Attribute) and value.as_string() == "sys.version_info":
-                return True
-
-        return False
-
-    def is_typing_guard(self) -> bool:
-        """Return True if IF stmt is a typing guard.
-
-        >>> import astroid
-        >>> node = astroid.extract_node('''
-        from typing import TYPE_CHECKING
-        if TYPE_CHECKING:
-            from xyz import a
-        ''')
-        >>> node.is_typing_guard()
-        True
-        """
-        warnings.warn(
-            "The 'is_typing_guard' function is deprecated and will be removed in astroid 3.0.0 "
-            "It has been moved to pylint and can be imported from 'pylint.checkers.utils' "
-            "starting with pylint 2.12",
-            DeprecationWarning,
-            stacklevel=2,
-        )
-        return isinstance(
-            self.test, (Name, Attribute)
-        ) and self.test.as_string().endswith("TYPE_CHECKING")
-
 
 class IfExp(NodeNG):
     """Class representing an :class:`ast.IfExp` node.
diff --git a/tests/test_nodes.py b/tests/test_nodes.py
index 1d8d67a049..aabd26119e 100644
--- a/tests/test_nodes.py
+++ b/tests/test_nodes.py
@@ -338,66 +338,6 @@ def test_block_range(self) -> None:
         self.assertEqual(self.astroid.body[1].orelse[0].block_range(7), (7, 8))
         self.assertEqual(self.astroid.body[1].orelse[0].block_range(8), (8, 8))
 
-    @staticmethod
-    @pytest.mark.filterwarnings("ignore:.*is_sys_guard:DeprecationWarning")
-    def test_if_sys_guard() -> None:
-        code = builder.extract_node(
-            """
-        import sys
-        if sys.version_info > (3, 8):  #@
-            pass
-
-        if sys.version_info[:2] > (3, 8):  #@
-            pass
-
-        if sys.some_other_function > (3, 8):  #@
-            pass
-        """
-        )
-        assert isinstance(code, list) and len(code) == 3
-
-        assert isinstance(code[0], nodes.If)
-        assert code[0].is_sys_guard() is True
-        assert isinstance(code[1], nodes.If)
-        assert code[1].is_sys_guard() is True
-
-        assert isinstance(code[2], nodes.If)
-        assert code[2].is_sys_guard() is False
-
-    @staticmethod
-    @pytest.mark.filterwarnings("ignore:.*is_typing_guard:DeprecationWarning")
-    def test_if_typing_guard() -> None:
-        code = builder.extract_node(
-            """
-        import typing
-        import typing as t
-        from typing import TYPE_CHECKING
-
-        if typing.TYPE_CHECKING:  #@
-            pass
-
-        if t.TYPE_CHECKING:  #@
-            pass
-
-        if TYPE_CHECKING:  #@
-            pass
-
-        if typing.SOME_OTHER_CONST:  #@
-            pass
-        """
-        )
-        assert isinstance(code, list) and len(code) == 4
-
-        assert isinstance(code[0], nodes.If)
-        assert code[0].is_typing_guard() is True
-        assert isinstance(code[1], nodes.If)
-        assert code[1].is_typing_guard() is True
-        assert isinstance(code[2], nodes.If)
-        assert code[2].is_typing_guard() is True
-
-        assert isinstance(code[3], nodes.If)
-        assert code[3].is_typing_guard() is False
-
 
 class TryExceptNodeTest(_NodeTest):
     CODE = """