diff --git a/Include/internal/pycore_opcode_metadata.h b/Include/internal/pycore_opcode_metadata.h
index d63c8df8ca6690..81dde66a6f26c2 100644
--- a/Include/internal/pycore_opcode_metadata.h
+++ b/Include/internal/pycore_opcode_metadata.h
@@ -2148,7 +2148,7 @@ const struct opcode_metadata _PyOpcode_opcode_metadata[266] = {
     [UNARY_NOT] = { true, INSTR_FMT_IX, HAS_PURE_FLAG },
     [UNPACK_EX] = { true, INSTR_FMT_IB, HAS_ARG_FLAG | HAS_ERROR_FLAG | HAS_ESCAPES_FLAG },
     [UNPACK_SEQUENCE] = { true, INSTR_FMT_IBC, HAS_ARG_FLAG | HAS_ERROR_FLAG | HAS_ESCAPES_FLAG },
-    [UNPACK_SEQUENCE_LIST] = { true, INSTR_FMT_IBC, HAS_ARG_FLAG | HAS_DEOPT_FLAG | HAS_ESCAPES_FLAG },
+    [UNPACK_SEQUENCE_LIST] = { true, INSTR_FMT_IBC, HAS_ARG_FLAG | HAS_DEOPT_FLAG },
     [UNPACK_SEQUENCE_TUPLE] = { true, INSTR_FMT_IBC, HAS_ARG_FLAG | HAS_DEOPT_FLAG },
     [UNPACK_SEQUENCE_TWO_TUPLE] = { true, INSTR_FMT_IBC, HAS_ARG_FLAG | HAS_DEOPT_FLAG },
     [WITH_EXCEPT_START] = { true, INSTR_FMT_IX, HAS_ERROR_FLAG | HAS_ESCAPES_FLAG },
diff --git a/Include/internal/pycore_uop_metadata.h b/Include/internal/pycore_uop_metadata.h
index 1825bb3a5abc80..89fce193f40bd8 100644
--- a/Include/internal/pycore_uop_metadata.h
+++ b/Include/internal/pycore_uop_metadata.h
@@ -112,7 +112,7 @@ const uint16_t _PyUop_Flags[MAX_UOP_ID+1] = {
     [_UNPACK_SEQUENCE] = HAS_ARG_FLAG | HAS_ERROR_FLAG | HAS_ESCAPES_FLAG,
     [_UNPACK_SEQUENCE_TWO_TUPLE] = HAS_ARG_FLAG | HAS_DEOPT_FLAG,
     [_UNPACK_SEQUENCE_TUPLE] = HAS_ARG_FLAG | HAS_DEOPT_FLAG,
-    [_UNPACK_SEQUENCE_LIST] = HAS_ARG_FLAG | HAS_DEOPT_FLAG | HAS_ESCAPES_FLAG,
+    [_UNPACK_SEQUENCE_LIST] = HAS_ARG_FLAG | HAS_DEOPT_FLAG,
     [_UNPACK_EX] = HAS_ARG_FLAG | HAS_ERROR_FLAG | HAS_ESCAPES_FLAG,
     [_STORE_ATTR] = HAS_ARG_FLAG | HAS_NAME_FLAG | HAS_ERROR_FLAG | HAS_ESCAPES_FLAG,
     [_DELETE_ATTR] = HAS_ARG_FLAG | HAS_NAME_FLAG | HAS_ERROR_FLAG | HAS_ESCAPES_FLAG,
diff --git a/Python/bytecodes.c b/Python/bytecodes.c
index c07ec42ec68f8b..e96674c3502ef1 100644
--- a/Python/bytecodes.c
+++ b/Python/bytecodes.c
@@ -1438,14 +1438,9 @@ dummy_func(
         inst(UNPACK_SEQUENCE_LIST, (unused/1, seq -- values[oparg])) {
             PyObject *seq_o = PyStackRef_AsPyObjectBorrow(seq);
             DEOPT_IF(!PyList_CheckExact(seq_o));
-            #ifdef Py_GIL_DISABLED
-            PyCriticalSection cs;
-            PyCriticalSection_Begin(&cs, seq_o);
-            #endif
+            DEOPT_IF(!LOCK_OBJECT(seq_o));
             if (PyList_GET_SIZE(seq_o) != oparg) {
-                #ifdef Py_GIL_DISABLED
-                PyCriticalSection_End(&cs);
-                #endif
+                UNLOCK_OBJECT(seq_o);
                 DEOPT_IF(true);
             }
             STAT_INC(UNPACK_SEQUENCE, hit);
@@ -1453,9 +1448,7 @@ dummy_func(
             for (int i = oparg; --i >= 0; ) {
                 *values++ = PyStackRef_FromPyObjectNew(items[i]);
             }
-            #ifdef Py_GIL_DISABLED
-            PyCriticalSection_End(&cs);
-            #endif
+            UNLOCK_OBJECT(seq_o);
             DECREF_INPUTS();
         }
 
diff --git a/Python/executor_cases.c.h b/Python/executor_cases.c.h
index c91257b06cad11..580814657608db 100644
--- a/Python/executor_cases.c.h
+++ b/Python/executor_cases.c.h
@@ -1728,18 +1728,12 @@
                 UOP_STAT_INC(uopcode, miss);
                 JUMP_TO_JUMP_TARGET();
             }
-            #ifdef Py_GIL_DISABLED
-            PyCriticalSection cs;
-            _PyFrame_SetStackPointer(frame, stack_pointer);
-            PyCriticalSection_Begin(&cs, seq_o);
-            stack_pointer = _PyFrame_GetStackPointer(frame);
-            #endif
+            if (!LOCK_OBJECT(seq_o)) {
+                UOP_STAT_INC(uopcode, miss);
+                JUMP_TO_JUMP_TARGET();
+            }
             if (PyList_GET_SIZE(seq_o) != oparg) {
-                #ifdef Py_GIL_DISABLED
-                _PyFrame_SetStackPointer(frame, stack_pointer);
-                PyCriticalSection_End(&cs);
-                stack_pointer = _PyFrame_GetStackPointer(frame);
-                #endif
+                UNLOCK_OBJECT(seq_o);
                 if (true) {
                     UOP_STAT_INC(uopcode, miss);
                     JUMP_TO_JUMP_TARGET();
@@ -1750,11 +1744,7 @@
             for (int i = oparg; --i >= 0; ) {
                 *values++ = PyStackRef_FromPyObjectNew(items[i]);
             }
-            #ifdef Py_GIL_DISABLED
-            _PyFrame_SetStackPointer(frame, stack_pointer);
-            PyCriticalSection_End(&cs);
-            stack_pointer = _PyFrame_GetStackPointer(frame);
-            #endif
+            UNLOCK_OBJECT(seq_o);
             PyStackRef_CLOSE(seq);
             stack_pointer += -1 + oparg;
             assert(WITHIN_STACK_BOUNDS());
diff --git a/Python/generated_cases.c.h b/Python/generated_cases.c.h
index 45bcc4242af9d7..e1f951558de7da 100644
--- a/Python/generated_cases.c.h
+++ b/Python/generated_cases.c.h
@@ -8040,18 +8040,9 @@
             values = &stack_pointer[-1];
             PyObject *seq_o = PyStackRef_AsPyObjectBorrow(seq);
             DEOPT_IF(!PyList_CheckExact(seq_o), UNPACK_SEQUENCE);
-            #ifdef Py_GIL_DISABLED
-            PyCriticalSection cs;
-            _PyFrame_SetStackPointer(frame, stack_pointer);
-            PyCriticalSection_Begin(&cs, seq_o);
-            stack_pointer = _PyFrame_GetStackPointer(frame);
-            #endif
+            DEOPT_IF(!LOCK_OBJECT(seq_o), UNPACK_SEQUENCE);
             if (PyList_GET_SIZE(seq_o) != oparg) {
-                #ifdef Py_GIL_DISABLED
-                _PyFrame_SetStackPointer(frame, stack_pointer);
-                PyCriticalSection_End(&cs);
-                stack_pointer = _PyFrame_GetStackPointer(frame);
-                #endif
+                UNLOCK_OBJECT(seq_o);
                 DEOPT_IF(true, UNPACK_SEQUENCE);
             }
             STAT_INC(UNPACK_SEQUENCE, hit);
@@ -8059,11 +8050,7 @@
             for (int i = oparg; --i >= 0; ) {
                 *values++ = PyStackRef_FromPyObjectNew(items[i]);
             }
-            #ifdef Py_GIL_DISABLED
-            _PyFrame_SetStackPointer(frame, stack_pointer);
-            PyCriticalSection_End(&cs);
-            stack_pointer = _PyFrame_GetStackPointer(frame);
-            #endif
+            UNLOCK_OBJECT(seq_o);
             PyStackRef_CLOSE(seq);
             stack_pointer += -1 + oparg;
             assert(WITHIN_STACK_BOUNDS());