diff --git a/misc/analyze_cache.py b/misc/analyze_cache.py
index e5ccc8456862..8b805d8da0bc 100644
--- a/misc/analyze_cache.py
+++ b/misc/analyze_cache.py
@@ -89,7 +89,7 @@ def compress(chunk: JsonDict) -> JsonDict:
     cache: dict[int, JsonDict] = {}
     counter = 0
 
-    def helper(chunk: Any) -> Any:
+    def helper(chunk: JsonDict) -> JsonDict:
         nonlocal counter
         if not isinstance(chunk, dict):
             return chunk
@@ -121,7 +121,7 @@ def helper(chunk: Any) -> Any:
 def decompress(chunk: JsonDict) -> JsonDict:
     cache: dict[int, JsonDict] = {}
 
-    def helper(chunk: Any) -> Any:
+    def helper(chunk: JsonDict) -> JsonDict:
         if not isinstance(chunk, dict):
             return chunk
         if ".id" in chunk:
diff --git a/misc/incremental_checker.py b/misc/incremental_checker.py
index 3f5393717ba6..3c1288e4eeb5 100755
--- a/misc/incremental_checker.py
+++ b/misc/incremental_checker.py
@@ -197,7 +197,9 @@ def stop_daemon() -> None:
 def load_cache(incremental_cache_path: str = CACHE_PATH) -> JsonDict:
     if os.path.exists(incremental_cache_path):
         with open(incremental_cache_path) as stream:
-            return json.load(stream)
+            cache = json.load(stream)
+            assert isinstance(cache, dict)
+            return cache
     else:
         return {}
 
diff --git a/misc/upload-pypi.py b/misc/upload-pypi.py
index 4d18b7d78ade..3c9b0b0736a6 100644
--- a/misc/upload-pypi.py
+++ b/misc/upload-pypi.py
@@ -32,12 +32,14 @@ def is_whl_or_tar(name: str) -> bool:
 def get_release_for_tag(tag: str) -> dict[str, Any]:
     with urlopen(f"{BASE}/{REPO}/releases/tags/{tag}") as f:
         data = json.load(f)
+    assert isinstance(data, dict)
     assert data["tag_name"] == tag
     return data
 
 
 def download_asset(asset: dict[str, Any], dst: Path) -> Path:
     name = asset["name"]
+    assert isinstance(name, str)
     download_url = asset["browser_download_url"]
     assert is_whl_or_tar(name)
     with urlopen(download_url) as src_file:
diff --git a/mypy/build.py b/mypy/build.py
index 4ba66a511a5b..f5ebdf52d941 100644
--- a/mypy/build.py
+++ b/mypy/build.py
@@ -1123,6 +1123,7 @@ def read_deps_cache(manager: BuildManager, graph: Graph) -> dict[str, FgDepMeta]
         return None
 
     module_deps_metas = deps_meta["deps_meta"]
+    assert isinstance(module_deps_metas, dict)
     if not manager.options.skip_cache_mtime_checks:
         for id, meta in module_deps_metas.items():
             try:
@@ -1167,6 +1168,7 @@ def _load_json_file(
         )
         return None
     else:
+        assert isinstance(result, dict)
         return result
 
 
diff --git a/mypy/dmypy_server.py b/mypy/dmypy_server.py
index 48d1df8f4d58..c9b622c768b9 100644
--- a/mypy/dmypy_server.py
+++ b/mypy/dmypy_server.py
@@ -267,7 +267,9 @@ def run_command(self, command: str, data: dict[str, object]) -> dict[str, object
                 # Only the above commands use some error formatting.
                 del data["is_tty"]
                 del data["terminal_width"]
-            return method(self, **data)
+            ret = method(self, **data)
+            assert isinstance(ret, dict)
+            return ret
 
     # Command functions (run in the server via RPC).
 
diff --git a/mypy/fastparse.py b/mypy/fastparse.py
index f1f85722afb9..0c80803d84d3 100644
--- a/mypy/fastparse.py
+++ b/mypy/fastparse.py
@@ -305,6 +305,7 @@ def parse(
     if raise_on_error and errors.is_errors():
         errors.raise_error()
 
+    assert isinstance(tree, MypyFile)
     return tree
 
 
@@ -1632,7 +1633,9 @@ def visit_ExtSlice(self, n: ast3.ExtSlice) -> TupleExpr:
     # Index(expr value)
     def visit_Index(self, n: Index) -> Node:
         # cast for mypyc's benefit on Python 3.9
-        return self.visit(cast(Any, n).value)
+        value = self.visit(cast(Any, n).value)
+        assert isinstance(value, Node)
+        return value
 
     # Match(expr subject, match_case* cases) # python 3.10 and later
     def visit_Match(self, n: Match) -> MatchStmt:
@@ -1762,7 +1765,9 @@ def visit(self, node: AST | None) -> ProperType | None:
             method = "visit_" + node.__class__.__name__
             visitor = getattr(self, method, None)
             if visitor is not None:
-                return visitor(node)
+                typ = visitor(node)
+                assert isinstance(typ, ProperType)
+                return typ
             else:
                 return self.invalid_type(node)
         finally:
@@ -1949,7 +1954,9 @@ def visit_Bytes(self, n: Bytes) -> Type:
 
     def visit_Index(self, n: ast3.Index) -> Type:
         # cast for mypyc's benefit on Python 3.9
-        return self.visit(cast(Any, n).value)
+        value = self.visit(cast(Any, n).value)
+        assert isinstance(value, Type)
+        return value
 
     def visit_Slice(self, n: ast3.Slice) -> Type:
         return self.invalid_type(n, note="did you mean to use ',' instead of ':' ?")
diff --git a/mypy/ipc.py b/mypy/ipc.py
index 8e693169ab36..db775935ac7a 100644
--- a/mypy/ipc.py
+++ b/mypy/ipc.py
@@ -270,4 +270,6 @@ def connection_name(self) -> str:
         if sys.platform == "win32":
             return self.name
         else:
-            return self.sock.getsockname()
+            name = self.sock.getsockname()
+            assert isinstance(name, str)
+            return name
diff --git a/mypy/literals.py b/mypy/literals.py
index 43425755aae8..9d91cf728b06 100644
--- a/mypy/literals.py
+++ b/mypy/literals.py
@@ -173,7 +173,7 @@ def visit_op_expr(self, e: OpExpr) -> Key:
         return ("Binary", e.op, literal_hash(e.left), literal_hash(e.right))
 
     def visit_comparison_expr(self, e: ComparisonExpr) -> Key:
-        rest: Any = tuple(e.operators)
+        rest: tuple[str | Key | None, ...] = tuple(e.operators)
         rest += tuple(literal_hash(o) for o in e.operands)
         return ("Comparison",) + rest
 
@@ -182,7 +182,7 @@ def visit_unary_expr(self, e: UnaryExpr) -> Key:
 
     def seq_expr(self, e: ListExpr | TupleExpr | SetExpr, name: str) -> Key | None:
         if all(literal(x) == LITERAL_YES for x in e.items):
-            rest: Any = tuple(literal_hash(x) for x in e.items)
+            rest: tuple[Key | None, ...] = tuple(literal_hash(x) for x in e.items)
             return (name,) + rest
         return None
 
@@ -191,7 +191,7 @@ def visit_list_expr(self, e: ListExpr) -> Key | None:
 
     def visit_dict_expr(self, e: DictExpr) -> Key | None:
         if all(a and literal(a) == literal(b) == LITERAL_YES for a, b in e.items):
-            rest: Any = tuple(
+            rest: tuple[Key | None, ...] = tuple(
                 (literal_hash(a) if a else None, literal_hash(b)) for a, b in e.items
             )
             return ("Dict",) + rest
diff --git a/mypy/metastore.py b/mypy/metastore.py
index 8a8a3088ca76..16cbd5adc9c8 100644
--- a/mypy/metastore.py
+++ b/mypy/metastore.py
@@ -185,10 +185,14 @@ def _query(self, name: str, field: str) -> Any:
         return results[0][0]
 
     def getmtime(self, name: str) -> float:
-        return self._query(name, "mtime")
+        mtime = self._query(name, "mtime")
+        assert isinstance(mtime, float)
+        return mtime
 
     def read(self, name: str) -> str:
-        return self._query(name, "data")
+        data = self._query(name, "data")
+        assert isinstance(data, str)
+        return data
 
     def write(self, name: str, data: str, mtime: float | None = None) -> bool:
         import sqlite3
diff --git a/mypy/nodes.py b/mypy/nodes.py
index 4856ce3035e8..3dad19bc9064 100644
--- a/mypy/nodes.py
+++ b/mypy/nodes.py
@@ -3150,10 +3150,10 @@ class FakeInfo(TypeInfo):
     def __init__(self, msg: str) -> None:
         self.msg = msg
 
-    def __getattribute__(self, attr: str) -> None:
+    def __getattribute__(self, attr: str) -> type:
         # Handle __class__ so that isinstance still works...
         if attr == "__class__":
-            return object.__getattribute__(self, attr)
+            return object.__getattribute__(self, attr)  # type: ignore[no-any-return]
         raise AssertionError(object.__getattribute__(self, "msg"))
 
 
diff --git a/mypy/stubtest.py b/mypy/stubtest.py
index 6ad416fd2097..655ad56b8012 100644
--- a/mypy/stubtest.py
+++ b/mypy/stubtest.py
@@ -315,7 +315,7 @@ def _belongs_to_runtime(r: types.ModuleType, attr: str) -> bool:
         except Exception:
             return False
         if obj_mod is not None:
-            return obj_mod == r.__name__
+            return bool(obj_mod == r.__name__)
         return not isinstance(obj, types.ModuleType)
 
     runtime_public_contents = (
@@ -614,7 +614,7 @@ def get_type(arg: Any) -> str | None:
 
         def has_default(arg: Any) -> bool:
             if isinstance(arg, inspect.Parameter):
-                return arg.default != inspect.Parameter.empty
+                return bool(arg.default != inspect.Parameter.empty)
             if isinstance(arg, nodes.Argument):
                 return arg.kind.is_optional()
             raise AssertionError
diff --git a/mypy/test/data.py b/mypy/test/data.py
index e08b95fedbde..6a2b5558afeb 100644
--- a/mypy/test/data.py
+++ b/mypy/test/data.py
@@ -680,7 +680,9 @@ class DataFileCollector(pytest.Collector):
     def from_parent(  # type: ignore[override]
         cls, parent: DataSuiteCollector, *, name: str
     ) -> DataFileCollector:
-        return super().from_parent(parent, name=name)
+        collector = super().from_parent(parent, name=name)
+        assert isinstance(collector, DataFileCollector)
+        return collector
 
     def collect(self) -> Iterator[DataDrivenTestCase]:
         yield from split_test_cases(
diff --git a/mypy/types.py b/mypy/types.py
index 7fc933ce38ba..e642858797ca 100644
--- a/mypy/types.py
+++ b/mypy/types.py
@@ -869,7 +869,7 @@ def __init__(
 
     def accept(self, visitor: TypeVisitor[T]) -> T:
         assert isinstance(visitor, SyntheticTypeVisitor)
-        return visitor.visit_callable_argument(self)
+        return cast(T, visitor.visit_callable_argument(self))
 
     def serialize(self) -> JsonDict:
         assert False, "Synthetic types don't serialize"
@@ -894,7 +894,7 @@ def __init__(self, items: list[Type], line: int = -1, column: int = -1) -> None:
 
     def accept(self, visitor: TypeVisitor[T]) -> T:
         assert isinstance(visitor, SyntheticTypeVisitor)
-        return visitor.visit_type_list(self)
+        return cast(T, visitor.visit_type_list(self))
 
     def serialize(self) -> JsonDict:
         assert False, "Synthetic types don't serialize"
@@ -2365,7 +2365,7 @@ def simple_name(self) -> str:
 
     def accept(self, visitor: TypeVisitor[T]) -> T:
         assert isinstance(visitor, SyntheticTypeVisitor)
-        return visitor.visit_raw_expression_type(self)
+        return cast(T, visitor.visit_raw_expression_type(self))
 
     def serialize(self) -> JsonDict:
         assert False, "Synthetic types don't serialize"
@@ -2488,7 +2488,7 @@ def __init__(self, type: Type, line: int = -1, column: int = -1) -> None:
 
     def accept(self, visitor: TypeVisitor[T]) -> T:
         assert isinstance(visitor, SyntheticTypeVisitor)
-        return visitor.visit_star_type(self)
+        return cast(T, visitor.visit_star_type(self))
 
     def serialize(self) -> JsonDict:
         assert False, "Synthetic types don't serialize"
@@ -2630,7 +2630,7 @@ class EllipsisType(ProperType):
 
     def accept(self, visitor: TypeVisitor[T]) -> T:
         assert isinstance(visitor, SyntheticTypeVisitor)
-        return visitor.visit_ellipsis_type(self)
+        return cast(T, visitor.visit_ellipsis_type(self))
 
     def serialize(self) -> JsonDict:
         assert False, "Synthetic types don't serialize"
@@ -2739,7 +2739,7 @@ def __init__(self, fullname: str | None, args: list[Type], line: int) -> None:
 
     def accept(self, visitor: TypeVisitor[T]) -> T:
         assert isinstance(visitor, SyntheticTypeVisitor)
-        return visitor.visit_placeholder_type(self)
+        return cast(T, visitor.visit_placeholder_type(self))
 
     def serialize(self) -> str:
         # We should never get here since all placeholders should be replaced
diff --git a/mypy_self_check.ini b/mypy_self_check.ini
index 5dc497528fab..1e07a5332e59 100644
--- a/mypy_self_check.ini
+++ b/mypy_self_check.ini
@@ -1,23 +1,6 @@
 [mypy]
 
-warn_unused_configs = True
-disallow_any_generics = True
-disallow_subclassing_any = True
-disallow_untyped_calls = True
-disallow_untyped_defs = True
-disallow_incomplete_defs = True
-check_untyped_defs = True
-disallow_untyped_decorators = True
-no_implicit_optional = True
-warn_redundant_casts = True
-warn_unused_ignores = True
-no_implicit_reexport = True
-strict_equality = True
-strict_concatenate = True
-
-; This is the only setting in --strict that we don't have enabled
-warn_return_any = False
-
+strict = True
 warn_no_return = True
 strict_optional = True
 disallow_any_unimported = True
diff --git a/mypyc/analysis/dataflow.py b/mypyc/analysis/dataflow.py
index 824d64a1bf4b..21c4da8981d1 100644
--- a/mypyc/analysis/dataflow.py
+++ b/mypyc/analysis/dataflow.py
@@ -68,7 +68,7 @@ def __init__(
 
     def __str__(self) -> str:
         lines = []
-        lines.append("exits: %s" % sorted(self.exits, key=lambda e: e.label))
+        lines.append("exits: %s" % sorted(self.exits, key=lambda e: int(e.label)))
         lines.append("succ: %s" % self.succ)
         lines.append("pred: %s" % self.pred)
         return "\n".join(lines)
diff --git a/mypyc/irbuild/constant_fold.py b/mypyc/irbuild/constant_fold.py
index 08cf75d9e5ca..8d0a7fea5d90 100644
--- a/mypyc/irbuild/constant_fold.py
+++ b/mypyc/irbuild/constant_fold.py
@@ -80,7 +80,9 @@ def constant_fold_binary_int_op(op: str, left: int, right: int) -> int | None:
             return left >> right
     elif op == "**":
         if right >= 0:
-            return left**right
+            ret = left**right
+            assert isinstance(ret, int)
+            return ret
     return None