diff --git a/cpp/src/compile_spec.cpp b/cpp/src/compile_spec.cpp
index 3de2daa14a..0fe56265e7 100644
--- a/cpp/src/compile_spec.cpp
+++ b/cpp/src/compile_spec.cpp
@@ -36,13 +36,15 @@ CompileSpec::CompileSpec(torch::jit::IValue input_signature) {
   graph_inputs.input_signature = input_signature;
 }
 
-void to_internal_input_signature(torch::jit::IValue input_ivalue, torch::jit::IValue& converted_ivalue) {
+void to_internal_input_signature(torch::jit::IValue input_ivalue, torch::jit::IValue& converted_ivalue, int depth = 0) {
+  TORCHTRT_CHECK(
+      depth <= 2, "Input nesting depth exceeds max supported depth, use 1 level: [A, B], or 2 level: [A, (B, C)]")
   if (input_ivalue.isTuple()) {
     auto input_tuple = input_ivalue.toTuple();
     std::vector<torch::jit::IValue> converted_elements;
     for (auto item : input_tuple->elements()) {
       torch::jit::IValue converted_item;
-      to_internal_input_signature(item, converted_item);
+      to_internal_input_signature(item, converted_item, depth++);
       converted_elements.push_back(converted_item);
       auto tuple_ptr = c10::ivalue::Tuple::create(converted_elements);
       converted_ivalue = torch::jit::IValue(tuple_ptr);
@@ -53,7 +55,7 @@ void to_internal_input_signature(torch::jit::IValue input_ivalue, torch::jit::IV
     auto converted_elements = c10::impl::GenericList(type);
     for (auto item : input_list) {
       torch::jit::IValue converted_item;
-      to_internal_input_signature(item, converted_item);
+      to_internal_input_signature(item, converted_item, depth++);
       converted_elements.push_back(converted_item);
     }
     converted_ivalue = torch::jit::IValue(converted_elements);
diff --git a/py/torch_tensorrt/ts/_compile_spec.py b/py/torch_tensorrt/ts/_compile_spec.py
index 50ba9b4ed5..0e11d3bcd3 100644
--- a/py/torch_tensorrt/ts/_compile_spec.py
+++ b/py/torch_tensorrt/ts/_compile_spec.py
@@ -194,17 +194,22 @@ def _parse_torch_fallback(fallback_info: Dict[str, Any]) -> _ts_C.TorchFallback:
     return info
 
 
-def _parse_input_signature(input_signature: Any):
+def _parse_input_signature(input_signature: Any, depth: int = 0):
+    if depth > 2:
+        raise AssertionError(
+            "Input nesting depth exceeds max supported depth, use 1 level: [A, B], or 2 level: [A, (B, C)]"
+        )
+
     if isinstance(input_signature, tuple):
         input_list = []
         for item in input_signature:
-            input = _parse_input_signature(item)
+            input = _parse_input_signature(item, depth + 1)
             input_list.append(input)
         return tuple(input_list)
     elif isinstance(input_signature, list):
         input_list = []
         for item in input_signature:
-            input = _parse_input_signature(item)
+            input = _parse_input_signature(item, depth + 1)
             input_list.append(input)
         return input_list
     elif isinstance(input_signature, Input) or isinstance(