diff --git a/.github/workflows/prototype-transforms-tests-linux-gpu.yml b/.github/workflows/prototype-transforms-tests-linux-gpu.yml
new file mode 100644
index 00000000000..e5740886b22
--- /dev/null
+++ b/.github/workflows/prototype-transforms-tests-linux-gpu.yml
@@ -0,0 +1,70 @@
+name: Prototype transforms unit-tests on Linux GPU
+
+on:
+  pull_request:
+  push:
+    branches:
+      - nightly
+      - main
+      - release/*
+  workflow_dispatch:
+
+env:
+  CHANNEL: "nightly"
+
+jobs:
+  tests:
+    strategy:
+      matrix:
+        python_version: ["3.8"]
+        cuda_arch_version: ["11.6"]
+      fail-fast: false
+    uses: pytorch/test-infra/.github/workflows/linux_job.yml@main
+    with:
+      runner: linux.4xlarge.nvidia.gpu
+      repository: pytorch/vision
+      gpu-arch-type: cuda
+      gpu-arch-version: ${{ matrix.cuda_arch_version }}
+      timeout: 120
+      script: |
+        # Mark Build Directory Safe
+        git config --global --add safe.directory /__w/vision/vision
+
+        # Set up Environment Variables
+        export PYTHON_VERSION="${{ matrix.python_version }}"
+        export VERSION="${{ matrix.cuda_arch_version }}"
+        export CUDATOOLKIT="pytorch-cuda=${VERSION}"
+
+        # Set CHANNEL
+        if [[ (${GITHUB_EVENT_NAME} = 'pull_request' && (${GITHUB_BASE_REF} = 'release'*)) || (${GITHUB_REF} = 'refs/heads/release'*) ]]; then
+          export CHANNEL=test
+        else
+          export CHANNEL=nightly
+        fi
+
+        # Create Conda Env
+        conda create -yp ci_env python="${PYTHON_VERSION}" numpy libpng jpeg scipy
+        conda activate /work/ci_env
+
+        # Install PyTorch, Torchvision, and testing libraries
+        set -ex
+        conda install \
+          --yes \
+          -c "pytorch-${CHANNEL}" \
+          -c nvidia \
+          pytorch \
+          torchdata \
+          "${CUDATOOLKIT}"
+
+        python3 -c "import torch; exit(not torch.cuda.is_available())"
+          
+        python3 setup.py develop
+        python3 -m pip install pytest pytest-mock pytest-cov
+
+        # Run Tests
+        python3 -m torch.utils.collect_env
+        python3 -m pytest \
+            --durations=20 \
+            --cov=torchvision/prototype/transforms \
+            --cov-report=term-missing \
+            test/test_prototype_transforms*.py
diff --git a/test/prototype_transforms_kernel_infos.py b/test/prototype_transforms_kernel_infos.py
index 9d97b6ca701..ded888a4a00 100644
--- a/test/prototype_transforms_kernel_infos.py
+++ b/test/prototype_transforms_kernel_infos.py
@@ -1940,11 +1940,13 @@ def sample_inputs_adjust_contrast_video():
             closeness_kwargs={
                 **pil_reference_pixel_difference(),
                 **float32_vs_uint8_pixel_difference(2),
+                **cuda_vs_cpu_pixel_difference(),
             },
         ),
         KernelInfo(
             F.adjust_contrast_video,
             sample_inputs_fn=sample_inputs_adjust_contrast_video,
+            closeness_kwargs=cuda_vs_cpu_pixel_difference(),
         ),
     ]
 )